Document Detail

High-frequency sonography of temporary and permanent dermal fillers.
MedLine Citation:
PMID:  20636993     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Dermal fillers are used widely; some have a permanent effect, whereas others are temporary. The aim of this study is to describe the ultrasonographic features of permanent and temporary fillers injected into patients for cosmetic purposes. MATERIALS AND METHODS: Between December 2006 and April 2009, 36 subjects, aged 25-45, who had received lips or nasolabial fold filler augmentation, were enrolled for a high-frequency sonographic examination by a blinded investigator. The criteria for exclusion were a history of autoimmunity, infection, neoplastic diseases or episodes of local reactions to the injected filler. Twenty patients underwent a sonographic exam after the injection of a temporary filler (collagen or hyaluronic acid) by FRG; the rest were enrolled among patients seeking a consultation for further cosmetic reasons, but had been treated with an identifiable filler before. RESULTS: It was always possible to identify the filler at the site of injection. Seldom was it possible to discover a silent inflammatory reaction, otherwise unsuspected. The sonographic images differed according to the temporary or the permanent nature of the filler. CONCLUSION: Ultrasonography has proved to be a useful, non-invasive tool for the identification of the presence and type of the filler injected.
Francesca Romana Grippaudo; Mauro Mattei
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)     Volume:  16     ISSN:  1600-0846     ISO Abbreviation:  Skin Res Technol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-19     Completed Date:  2010-10-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504453     Medline TA:  Skin Res Technol     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  265-9     Citation Subset:  IM    
Plastic Surgery Unit, 2nd Medical Faculty, Sapienza University of Rome, Rome, Italy.
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MeSH Terms
Acrylic Resins / administration & dosage,  pharmacokinetics
Biocompatible Materials / administration & dosage*,  pharmacokinetics
Collagen / administration & dosage*,  pharmacokinetics
Cosmetic Techniques / instrumentation*
DEAE-Dextran / administration & dosage,  pharmacokinetics
Dermis / metabolism,  pathology,  ultrasonography*
Hyaluronic Acid / administration & dosage,  analogs & derivatives,  pharmacokinetics
Hydrogels / administration & dosage,  pharmacokinetics
Middle Aged
Skin Aging / drug effects,  pathology
Subcutaneous Fat / metabolism,  pathology,  ultrasonography
Ultrasonography / methods*
Reg. No./Substance:
0/Acrylic Resins; 0/Aquamid; 0/Biocompatible Materials; 0/Hydrogels; 0/Restylane; 0/dermicol-P35 27G; 0/polyacrylamide gels; 9004-61-9/Hyaluronic Acid; 9007-34-5/Collagen; 9015-73-0/DEAE-Dextran

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