| High-frequency oscillatory ventilation for infants and children with adult respiratory distress syndrome. | |
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MedLine Citation:
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PMID: 9151467 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two infants and two children suffered from severe hypoxemia, presenting as a ratio of arterial to alveolar PaO2 < 0.1, persisting for more than 3 hours in spite of high settings on conventional mechanical ventilator. Adult respiratory distress syndrome was diagnosed with the support of bilateral diffuse haziness on chest radiographs. High-frequency oscillatory ventilation with high-lung-volume strategy resulted in prompt decrease in oxygenation index and increase in ratio of arterial to alveolar P O2 in three (75%) of the 4 patients within 6 hours. After a mean duration of 96 hours, high-frequency oscillatory ventilation could be weaned off and conventional ventilation could be resumed at lower mean airway pressure in 3 patients. They continued to improve and finally recovered. The other one showed initially steady improvement on high-frequency oscillatory ventilation for 20 hours, but ultimately died of unresolved cytomegalovirus pneumonitis and intractable pulmonary hemorrhage. There were 2 episodes of pneumothorax developing during high-frequency oscillatory ventilation. After decreasing mean airway pressure and amplitude, the airleak resolved with chest tube insertion. We conclude that high-frequency oscillatory ventilation with high-lung-volume strategy may be an effective rescue therapy to relieve profound hypoxemia in infants and children with adult respiratory distress syndrome. |
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Authors:
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J R Tang; K I Yau; H H Shih |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Zhonghua Minguo xiao er ke yi xue hui za zhi [Journal]. Zhonghua Minguo xiao er ke yi xue hui Volume: 38 ISSN: 0001-6578 ISO Abbreviation: Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi Publication Date: 1997 Mar-Apr |
Date Detail:
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Created Date: 1997-07-03 Completed Date: 1997-07-03 Revised Date: 2008-02-12 |
Medline Journal Info:
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Nlm Unique ID: 16210470R Medline TA: Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi Country: TAIWAN |
Other Details:
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Languages: eng Pagination: 137-44 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, National Taiwan University Hospital, Taipei, R.O.C. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anoxia
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complications,
therapy Child Child, Preschool Female High-Frequency Ventilation / methods* Humans Infant Infant, Newborn Male Oxygen / blood Partial Pressure Respiratory Distress Syndrome, Adult / complications, therapy* Time Factors |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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