Document Detail


High-frequency QRS electrocardiogram predicts perfusion defects during myocardial perfusion imaging.
MedLine Citation:
PMID:  16387056     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Changes in high-frequency (HF) QRS components of the electrocardiogram (ECG) (150-250 Hz) are more sensitive than changes in conventional ST segments for detecting myocardial ischemia. We investigated the accuracy of 12-lead HF QRS ECG in detecting perfusion defects during adenosine tetrofosmin myocardial perfusion imaging (MPI). METHODS AND RESULTS: 12-lead HF QRS ECG recordings were obtained from 45 patients before and during adenosine technetium Tc 99m tetrofosmin MPI tests. Before the adenosine infusions, recordings of HF QRS were analyzed according to a morphologic score that incorporated the number, type, and location of reduced amplitude zones (RAZs) present in the 12 leads. During the adenosine infusions, recordings of HF QRS were analyzed according to the maximum percentage changes (in both the positive and negative directions) that occurred in root mean square voltage amplitudes within the 12 leads. The best set of prospective HF QRS criteria had a sensitivity of 94% and a specificity of 83% for correctly identifying the MPI result. The sensitivity of simultaneous ST-segment changes (18%) was significantly lower than that of any individual HF QRS criterion (P < .001). CONCLUSIONS: Analysis of 12-lead HF QRS ECG is highly sensitive and reasonably specific for detecting perfusion defects during adenosine MPI stress tests and significantly more sensitive than analysis of conventional ST segments.
Authors:
M Atiar Rahman; Alex Gedevanishvili; Yochai Birnbaum; Laura Sarmiento; Waralee Sattam; Walter B Kulecz; Todd T Schlegel
Related Documents :
7387816 - Effect of therapeutic dosage of lithium on the heart.
23535196 - Vaporizing thrombus with excimer laser before coronary stenting improves myocardial rep...
15364096 - Detecting acute myocardial infarction in the 12-lead ecg using hermite expansions and n...
23652366 - Lipoprotein(a) is an important factor to determine coronary artery plaque morphology in...
20588186 - The role of microrna in cardiac excitability.
16009786 - Angiotensin-converting enzyme inhibitors and calcium channel blockers for coronary hear...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2005-11-28
Journal Detail:
Title:  Journal of electrocardiology     Volume:  39     ISSN:  0022-0736     ISO Abbreviation:  J Electrocardiol     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-01-02     Completed Date:  2006-04-25     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  73-81     Citation Subset:  IM    
Affiliation:
MD Anderson Cancer Center, Houston, TX 77030, USA. amrahman@mdanderson.org
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adenosine / diagnostic use*
Aged
Chest Pain / diagnosis
Coronary Circulation / physiology*
Electrocardiography*
Exercise Test
False Positive Reactions
Female
Humans
Male
Middle Aged
Myocardial Ischemia / diagnosis*,  physiopathology,  radionuclide imaging
Organophosphorus Compounds / diagnostic use
Organotechnetium Compounds / diagnostic use
Preoperative Care
Radiopharmaceuticals / diagnostic use
Regression Analysis
Sensitivity and Specificity
Signal Processing, Computer-Assisted
Vasodilator Agents / diagnostic use*
Chemical
Reg. No./Substance:
0/Organophosphorus Compounds; 0/Organotechnetium Compounds; 0/Radiopharmaceuticals; 0/Vasodilator Agents; 0/technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane; 58-61-7/Adenosine
Comments/Corrections
Comment In:
J Electrocardiol. 2006 Jan;39(1):87   [PMID:  16387058 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Left ventricular mass by 12-lead electrocardiogram in healthy subjects: comparison to cardiac magnet...
Next Document:  P-wave body surface potential distribution in rats.