| High-flow, aortocaval fistulae: radiologic and histopathologic evaluation in a rat model. | |
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MedLine Citation:
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PMID: 6410747 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An animal model for a high-flow, aorta-to-vena cava fistula has been developed using microsurgical techniques in the rat. This model provides a means for histopathologic and angiographic evaluation of the natural evolution of major vessel, artery to vein fistulae. Data obtained from such a model may have relevance to the successful treatment of high-flow, head and neck fistulae using detachable intraarterial occlusive balloons. This microsurgical technique is unique, since it requires no intervening sutures or graft material that would alter the histopathologic process. After a series of such aortocaval fistulae were created, serial histologic and angiographic features were elucidated for intervals between 1 day and 6 months. Three stages of evolution are noted including: an initial hemorrhagic dissection phase; a subacute phase where organization of the thrombus and actual formation of a fistulous tract occurs; and a chronic phase characterized by pseudoaneurysm formation, arterialization of the vena cava, and proximal vasodilatation of the aorta. |
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Authors:
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R G Quisling; J P Mickle; W Ballinger |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: AJNR. American journal of neuroradiology Volume: 4 ISSN: 0195-6108 ISO Abbreviation: AJNR Am J Neuroradiol Publication Date: 1983 May-Jun |
Date Detail:
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Created Date: 1983-09-20 Completed Date: 1983-09-20 Revised Date: 2008-02-14 |
Medline Journal Info:
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Nlm Unique ID: 8003708 Medline TA: AJNR Am J Neuroradiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 369-73 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Aorta, Abdominal / pathology Aortic Diseases / pathology, radiography* Aortography Arteriovenous Fistula / pathology, radiography* Disease Models, Animal Rats Vena Cava, Inferior / pathology, radiography* |
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