Document Detail


High-dose loading with extended release quetiapine.
MedLine Citation:
PMID:  20831551     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Extended release quetiapine fumarate (quetiapine XR) was initiated at the recommended maximum dose 800 mg and maintained at the same dose in five patients with schizophrenia. Although the loadings of quetiapine XR were well tolerated in four patients in these five cases, one patient with a history of cerebral infarction developed serious side-effects, notably bladder distention and dizziness. This case series indicates that loading with maximum dose quetiapine XR may be tolerable and used safely in most schizophrenia patients with no other concurrent disease such as brain infarction.
Authors:
B-J Chae
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical pharmacy and therapeutics     Volume:  35     ISSN:  1365-2710     ISO Abbreviation:  J Clin Pharm Ther     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-09-13     Completed Date:  2010-12-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8704308     Medline TA:  J Clin Pharm Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  487-9     Citation Subset:  IM    
Affiliation:
Department of Psychiatry, Daedong Hospital, Dalseo-gu, Daegu, Korea. bjchae@korea.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Antipsychotic Agents / administration & dosage*,  adverse effects,  therapeutic use
Delayed-Action Preparations
Dibenzothiazepines / administration & dosage*,  adverse effects,  therapeutic use
Drug Administration Schedule
Female
Humans
Male
Middle Aged
Psychiatric Status Rating Scales
Schizophrenia / drug therapy
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antipsychotic Agents; 0/Delayed-Action Preparations; 0/Dibenzothiazepines; 0/quetiapine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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