Document Detail

High-dose cytosine arabinoside-induced symptomatic bradycardia.
MedLine Citation:
PMID:  21178637     Owner:  NLM     Status:  Publisher    
Cardiac complications of high-dose cytosine arabinoside (HiDAC), although rare, predominantly include pericarditis, pericardial effusion and cardiomyopathy (with concurrent use of cyclophosphamide). Clinically significant arrhythmias associated with HiDAC, although reported in the literature, are rare. The following case report has for the first time used the Naranjo Scale to document a high-probability association (definite adverse drug reaction) of cytarabine with symptomatic sinus bradycardia.
Siddharth A Wayangankar; Bhavin C Patel; Hiral D Parekh; Jennifer L Holter; Ralph Lazzara
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-12-21
Journal Detail:
Title:  Journal of cardiovascular medicine (Hagerstown, Md.)     Volume:  -     ISSN:  1558-2035     ISO Abbreviation:  -     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101259752     Medline TA:  J Cardiovasc Med (Hagerstown)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
aDepartment of Internal Medicine, USA bSection of Hematology and Oncology, USA cSection of Cardiovascular Diseases, University of Oklahoma, Oklahoma City, Oklahoma, USA.
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