| High density lipoprotein and other lipoproteins in normolipidaemic and hypertriglyceridaemic (type IV) men with coronary artery disease. | |
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MedLine Citation:
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PMID: 6800818 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim was to investigate whether a low concentration of high density lipoprotein (HDL) may be used as a risk indicator in normolipidaemic (n.l.) subjects, and whether a reduced HDL concentration constitutes an additional risk factor in hyperlipoproteinaemia. Eighty-two men with angiographically documented coronary artery disease (CAD) were studied. The majority of the CAD men was either n.l. (n = 38) or had type IV hyperlipoproteinaemia (n = 22). These two groups were compared separately to one group of healthy n.l. subjects (n = 44), and one group of healthy subjects with type IV hyperlipoproteinaemia (n = 29). In about 50% of n.l. CAD men the HDL-cholesterol (HDL-C) was lower than the 15th percentile (0.90 mmol/l) of n.l. controls, and about 65% of n.l. CAD men had ratios of HDL-C/total plasma cholesterol (C) lower than 0.17, the 15th percentile of n.l. controls. Almost all type IV subjects had reduced HDL-C levels and decreased ratios of HDL-C/C, whether they had obvious CAD or not. Thus, in normolipidaemia, but not in type IV hyperlipoproteinaemia, a low HDL-C level may be used as an additional risk factor for CAD development. |
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Authors:
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B Moberg; L Wallentin |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of clinical investigation Volume: 11 ISSN: 0014-2972 ISO Abbreviation: Eur. J. Clin. Invest. Publication Date: 1981 Dec |
Date Detail:
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Created Date: 1982-05-12 Completed Date: 1982-05-12 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0245331 Medline TA: Eur J Clin Invest Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 433-40 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Angina Pectoris / blood Cholesterol / blood* Cholesterol, HDL Coronary Disease / blood*, etiology Humans Hyperlipoproteinemia Type IV / blood* Lipoproteins, HDL / blood* Male Middle Aged Risk |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 0/Lipoproteins, HDL; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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