Document Detail


High-density lipoprotein cholesterol: a potential therapeutic target for prevention of coronary artery disease.
MedLine Citation:
PMID:  17215630     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
High-density lipoprotein cholesterol has an important role in the pathophysiology of coronary artery disease. High-density lipoprotein cholesterol is becoming an increasingly important prognostic and therapeutic target. The purpose of this paper is to review the biochemical pathways involved in reverse cholesterol transport and to discuss potential, clinically based high-density lipoprotein therapies that may contribute to reduction in risk of atherosclerosis.
Authors:
Alexander Chernobelsky; M Dominique Ashen; Roger S Blumenthal; Neil L Coplan
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Preventive cardiology     Volume:  10     ISSN:  1520-037X     ISO Abbreviation:  Prev Cardiol     Publication Date:  2007  
Date Detail:
Created Date:  2007-01-11     Completed Date:  2007-03-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9813731     Medline TA:  Prev Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  26-30     Citation Subset:  IM    
Affiliation:
Division of Cardiovascular Medicine, Department of Medicine, Lenox Hill Hospital, New York, NY 10021, USA.
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MeSH Terms
Descriptor/Qualifier:
ATP-Binding Cassette Transporters / metabolism
Anticholesteremic Agents / pharmacology
Biological Transport
Cholesterol Ester Transfer Proteins / antagonists & inhibitors,  metabolism
Cholesterol, HDL / blood,  metabolism*
Coronary Artery Disease / blood,  prevention & control*
Humans
Chemical
Reg. No./Substance:
0/ATP-Binding Cassette Transporters; 0/Anticholesteremic Agents; 0/CETP protein, human; 0/Cholesterol Ester Transfer Proteins; 0/Cholesterol, HDL

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