Document Detail


High-density lipoprotein cholesterol in coronary artery disease patients: is it as low as expected?
MedLine Citation:
PMID:  16330390     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Epidemiological studies demonstrated that the high-density lipoprotein (HDL) cholesterol levels in Turkish people are lower compared to other populations. In the present study, the HDL cholesterol levels in subjects with or without angiographically documented coronary artery disease (CAD) were compared to assess whether HDL cholesterol levels were as low as expected. METHODS: A total of 420 consecutive patients with age of > or =40 years (160 female, 260 male) undergoing coronary angiography were included in the study. Patients receiving fibric acid derivatives or niacin were excluded. Coronary artery disease group consisted of those patients with any atherosclerotic lesions in coronary angiography, and non-CAD group consisted of patients with no such lesions. RESULTS: Average HDL cholesterol levels were 45.0+/-10.5 mg/dl (44.4+/-10.9 mg/dl in men, 46.5+/-9.6 mg/dl in women) in CAD group, and 47.7+/-9.0 mg/dl (45.5+/-8.4 mg/dl in men, 48.9+/-9.2 mg/dl in women) in non-CAD group (p<0.05). CONCLUSION: Compared to non-CAD patients, patients with CAD had lower HDL cholesterol levels, but in general HDL cholesterol levels were not as low as to be expected from epidemiological studies.
Authors:
Mehmet Uzunlulu; Aytekin O?uz; K?r?at Tigen
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology     Volume:  5     ISSN:  1302-8723     ISO Abbreviation:  Anadolu Kardiyol Derg     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-12-06     Completed Date:  2006-04-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101095069     Medline TA:  Anadolu Kardiyol Derg     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  268-70     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, SSK G?ztepe Training Hospital, 34732, Istanbul, Turkey. mehmetuzunlulu@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Angiography
Biological Markers / blood
Case-Control Studies
Cholesterol, HDL / blood*
Coronary Artery Disease / blood*,  epidemiology*
Female
Humans
Lipid Metabolism*
Male
Middle Aged
Risk Factors
Turkey / epidemiology
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Cholesterol, HDL
Comments/Corrections
Comment In:
Anadolu Kardiyol Derg. 2006 Mar;6(1):92-3; author reply 93   [PMID:  16524815 ]
Anadolu Kardiyol Derg. 2006 Mar;6(1):94-6; author reply 96   [PMID:  16524816 ]

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