Document Detail

High calcium intake blunts pregnancy-induced increases in maternal blood lead.
MedLine Citation:
PMID:  11396696     Owner:  NLM     Status:  MEDLINE    
In pregnant women with low exposure to lead, high intakes of calcium (>2,000 mg/day) decreased the serum concentration of lead, which could potentially minimize fetal exposure to lead. This is twice the amount of calcium recommended for women during pregnancy and approaches the Upper Level for calcium of 2,500 mg/day. The mechanism by which high calcium intake blunts pregnancy-induced increases in maternal blood lead may involve decreased lead absorption in the intestine or decreased maternal bone resorption with subsequent release of lead. Either mechanism could decrease maternal blood concentrations of lead and potentially limit fetal accumulation of lead.
M A Johnson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nutrition reviews     Volume:  59     ISSN:  0029-6643     ISO Abbreviation:  Nutr. Rev.     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-06-08     Completed Date:  2001-07-05     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0376405     Medline TA:  Nutr Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  152-6     Citation Subset:  IM    
Department of Foods and Nutrition, The University of Georgia, Athens 30602-3622, USA.
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MeSH Terms
Calcium, Dietary / administration & dosage*
Embryonic and Fetal Development
Intestinal Absorption
Lead / blood*
Lead Poisoning / embryology,  prevention & control
Maternal Exposure
Pregnancy / blood*
Pregnancy Complications / blood,  prevention & control
Reg. No./Substance:
0/Calcium, Dietary; 7439-92-1/Lead

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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