Document Detail

High biliary excretion levels of quercetin metabolites after administration of a quercetin glycoside in conscious bile duct cannulated rats.
MedLine Citation:
PMID:  19661706     Owner:  NLM     Status:  MEDLINE    
Biliary excretion of quercetin metabolites in conscious rats was biphasic, a high peak within 3 h and a lower peak for next 6 h, after duodenal administration of soluble quercetin glycosides. We also found much higher biliary excretion of quercetin metabolites than urinary excretion on feeding a quercetin glycoside diet. These results suggest high levels of enterohepatic circulation of quercetin metabolites.
Noriko Matsukawa; Megumi Matsumoto; Hiroshi Hara
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Publication Detail:
Type:  Journal Article     Date:  2009-08-07
Journal Detail:
Title:  Bioscience, biotechnology, and biochemistry     Volume:  73     ISSN:  1347-6947     ISO Abbreviation:  Biosci. Biotechnol. Biochem.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-08-24     Completed Date:  2009-11-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205717     Medline TA:  Biosci Biotechnol Biochem     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1863-5     Citation Subset:  IM    
Laboratory of Nutritional Biochemistry, Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University, Sapporo, Hokkaido, Japan.
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MeSH Terms
Bile / drug effects*,  secretion*
Bile Ducts*
Glycosides / administration & dosage*,  pharmacology*
Quercetin / administration & dosage,  analogs & derivatives*,  metabolism*,  pharmacology,  secretion
Rats, Sprague-Dawley
Reg. No./Substance:
0/Glycosides; 117-39-5/Quercetin

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