Document Detail


High antioxidant potatoes: Acute in vivo antioxidant source and hypotensive agent in humans after supplementation to hypertensive subjects.
MedLine Citation:
PMID:  22224463     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Potatoes have the highest daily per capita consumption of all the vegetables in the US diet. Pigmented potatoes contain high concentrations of antioxidants, including phenolic acids, anthocyanins, and carotenoids. In a single dose study we gave 6-8 microwaved potatoes with skins or a comparable amount of refined starch as cooked biscuits to 8 normal fasting subjects and took repeated samples of blood over an 8-hour period. Plasma antioxidant capacity was measured by Ferric Reducing Antioxidant Power (FRAP). A 24-hour urine was taken before and after each regimen. Urine antioxidant capacity due to polyphenol was measured by Folin reagent after correction for non-phenolic interferences with a solid phase (Polyclar) procedure. Potato caused an increase in plasma and urine antioxidant capacity whereas refined potato starch caused a decrease in both, i.e. was a pro-oxidant. In a crossover study 18 hypertensive subjects with an average BMI of 29 were given either 6-8 small microwaved purple potatoes twice daily or no potatoes for 4 weeks and then given the other regimen for another 4 weeks. There was no significant effect of potato on fasting plasma glucose, lipids, HbA1c. There was no significant body weight increase. Diastolic blood pressure significantly decreased 4.3%, a 4 mm reduction. Systolic blood pressure decreased 3.5%, a 5 mm reduction. This blood pressure drop occurred in spite of the fact that 14/18 subjects were taking antihypertensive drugs. This is the first study to investigate the effect of potatoes on blood pressure. Thus purple potatoes are an effective hypotensive agent and lower the risk of heart disease and stroke in hypertensive subjects without weight gain.
Authors:
Joe A Vinson; Cheryil A Demkosksy; Duroy A Navarre; Melissa A Smyda
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-5
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  -     ISSN:  1520-5118     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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