Document Detail

High amount of dietary carbohydrate does not cause an adaptational increase of stimulated human pancreatic amylase secretion.
MedLine Citation:
PMID:  2471755     Owner:  NLM     Status:  MEDLINE    
In order to investigate whether the human pancreas is capable of adapting to a diet with high-carbohydrate, low-fat, and normal protein content, 10 healthy volunteers were given a defined elemental diet (60% of calories as carbohydrates, 22% as fat, and 18% as protein) for 7 d. For the next 7 d they received an elemental diet with a further increased carbohydrate content (76% of calories) and a decreased fat content (10% of calories). A complete secretin-pancreozymin test was carried out at the end of the first wk and at d 14. The results show that an increase in dietary carbohydrate does not provoke an adaptational response of stimulated secretion rates of amylase, trypsin, and chymotrypsin in humans, as expected from animal experiments.
R M Liehr; M E Herrmann; C Emde; R Hopert; E O Riecken
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of pancreatology : official journal of the International Association of Pancreatology     Volume:  4     ISSN:  0169-4197     ISO Abbreviation:  Int. J. Pancreatol.     Publication Date:  1989 May 
Date Detail:
Created Date:  1989-07-27     Completed Date:  1989-07-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8703511     Medline TA:  Int J Pancreatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  419-30     Citation Subset:  IM    
Medizinische Klinik, Klinikum Steglitz der FU Berlin, FRG.
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MeSH Terms
Amylases / secretion*
Bicarbonates / secretion
Cholesterol / blood
Chymotrypsin / secretion
Dietary Carbohydrates / administration & dosage,  pharmacology*
Enteral Nutrition
Nutritional Status
Pancreas / drug effects,  enzymology*
Prealbumin / analysis
Reference Values
Trypsin / secretion
Urea / blood
Reg. No./Substance:
0/Bicarbonates; 0/Dietary Carbohydrates; 0/Prealbumin; 57-13-6/Urea; 57-88-5/Cholesterol; EC 3.2.1.-/Amylases; EC; EC

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