| High altitude residence during pregnancy alters cytokine and catecholamine levels. | |
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MedLine Citation:
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PMID: 12516658 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study assessed the impact of high altitude residence during pregnancy on parameters of maternal immune and endocrine system function. Urinary catecholamines, and serum cytokines, estriol, and cortisol were assessed during pregnancy in women living at moderate or high altitude. Women residing at high altitude exhibited elevated levels of proinflammatory cytokines only during pregnancy, and tended to have higher levels of catecholamines during pregnancy than women living at lower altitude. These data suggest that the combination of high altitude and pregnancy alters the maternal neural-immune axis in a manner that may predispose women to suboptimal birth outcomes. |
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Authors:
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Mary E Coussons-Read; Robert S Mazzeo; Margaret H Whitford; Mischel Schmitt; Lorna G Moore; Stacy Zamudio |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: American journal of reproductive immunology (New York, N.Y. : 1989) Volume: 48 ISSN: 1046-7408 ISO Abbreviation: Am. J. Reprod. Immunol. Publication Date: 2002 Nov |
Date Detail:
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Created Date: 2003-01-08 Completed Date: 2003-04-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8912860 Medline TA: Am J Reprod Immunol Country: Denmark |
Other Details:
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Languages: eng Pagination: 344-54 Citation Subset: IM |
Affiliation:
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Department of Psychology and Program in Health and Behavioral Sciences, University of Colorado at Denver, Denver, CO 80217, USA. mary.coussons-read@cudenver.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Altitude* Catecholamines / urine* Cytokines / blood* Estradiol / blood Female Humans Hydrocortisone / blood Pregnancy / immunology*, metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Catecholamines; 0/Cytokines; 50-23-7/Hydrocortisone; 50-28-2/Estradiol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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