| High-resolution solid-state manometry of the upper and lower esophageal sphincters during anesthesia induction: a comparison between obese and non-obese patients. | |
| | |
MedLine Citation:
|
PMID: 20522705 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The prevalence of obesity has increased dramatically in recent decades. The gastrointestinal changes associated with obesity have clinical significance for the anesthesiologist in the perioperative period. The lower esophageal sphincter and the upper esophageal sphincter play a central role in preventing regurgitation and aspiration. The effects of increased intra-abdominal pressure during anesthesia on the lower esophageal sphincter and the upper esophageal sphincter in obese patients are unknown. In the present study we evaluated, with high-resolution solid-state manometry, the upper esophageal sphincter, lower esophageal sphincter, and barrier pressure (BrP) (lower esophageal pressure--gastric pressure) in obese patients during anesthesia induction and compared them with pressures in non-obese patients. METHODS: We studied 28 patients, ages 18 to 72 years, 14 with a body mass index > or = 35 kg/m(2), who were undergoing laparoscopic gastric bypass, and 14 with a body mass index < or = 30 kg/m(2), who were undergoing laparoscopic cholecystectomy, using high-resolution solid-state manometry. RESULTS: Upper esophageal sphincter pressure decreased during anesthesia induction in both groups. Lower esophageal sphincter pressure decreased in both groups during anesthesia induction, and it was significantly lower in obese patients than in non-obese patients. The BrP decreased in both groups and was significantly lower in the obese group than in the non-obese group. The BrP remained positive at all times in both groups. CONCLUSION: Lower esophageal sphincter and BrPs decreased in both obese and non-obese patients during anesthesia induction, but were significantly lower in obese patients. Although the BrP was significantly lower, it remained positive in all patients. |
| | |
Authors:
|
Alex de Leon; Sven-Egron Thörn; Magnus Wattwil |
Related Documents
:
|
9563975 - A study of the effect of renal pelvic and ureteric distention on the anorectal function... 1735315 - Influence of sleep on anal sphincteric pressure in health and after ileal pouch-anal an... 16984495 - The effects of tegaserod on oesophageal function and bolus transport in healthy volunte... 1545375 - Effects of a prostacyclin analog, u-68,215, on gastric acid secretion, gastric emptying... 18718025 - Inflammatory and transcriptional roles of poly (adp-ribose) polymerase in ventilator-in... 10855655 - Multicore myopathy: respiratory failure and paraspinal muscle contractures are importan... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-06-03 |
Journal Detail:
|
Title: Anesthesia and analgesia Volume: 111 ISSN: 1526-7598 ISO Abbreviation: Anesth. Analg. Publication Date: 2010 Jul |
Date Detail:
|
Created Date: 2010-06-25 Completed Date: 2010-07-12 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 1310650 Medline TA: Anesth Analg Country: United States |
Other Details:
|
Languages: eng Pagination: 149-53 Citation Subset: AIM; IM |
Affiliation:
|
Universitetssjukhuset Orebro, 70185 Orebro, Sweden. alex.deleon@orebroll.se |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Anesthesia* Body Weight / physiology Catheterization Cholecystectomy, Laparoscopic Data Interpretation, Statistical Esophageal Sphincter, Lower / physiology* Esophageal Sphincter, Upper / physiology* Female Gastric Bypass Humans Laparoscopy Male Manometry / methods* Middle Aged Obesity / physiopathology* Pharynx / physiology Pressure Stomach / physiology Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Transesophageal Echocardiographic Evaluation During Aortic Valve Repair Surgery.
Next Document: Lumbar Cerebrospinal Fluid Drainage for Thoracoabdominal Aortic Surgery: Rationale and Practical Con...