| High-resolution 3D unenhanced ECG-gated respiratory-navigated MR angiography of the renal arteries: comparison with contrast-enhanced MR angiography. | |
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MedLine Citation:
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PMID: 21098205 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The aim of this study is to determine the diagnostic value of high-resolution 3D unenhanced ECG-gated respiratory-navigated MR angiography (MRA) of the renal arteries using a steady-state free precession (SSFP) technique in comparison with 1.0-molar contrast-enhanced MRA in patients with suspected renal artery stenosis. SUBJECTS AND METHODS: Forty-five consecutive patients underwent unenhanced MRA before contrast-enhanced MRA within the same session. We assessed examination time, image quality, renal artery architecture, and localization and severity of renal artery stenosis. RESULTS: Examination time was shorter for contrast-enhanced MRA (mean ± SD, 12 ± 3 minutes) than for unenhanced MRA (19 ± 3 minutes; p < 0.001). On a 5-point scale, the image quality was similar for contrast-enhanced MRA (3.8 ± 1.0) and unenhanced MRA (4.0 ± 1.3; p = 0.24). Contrast-enhanced MRA offered more assessable data sets than did unenhanced MRA (95% vs 90%); however, unenhanced MRA had more data sets with maximum image quality (49% vs 30%). There was moderate agreement in stenosis grading between both MRA techniques (κ = 0.51; p < 0.001), but in only one case (1.3%) we found mismatch of more than one severity stenosis grade (stenoses > 75%). Sensitivity, specificity, and positive and negative predictive values of unenhanced MRA to detect renal artery stenoses greater than 50% were 75%, 99%, 75%, and 99%, respectively. CONCLUSION: We show that SSFP 3D unenhanced MRA is a very promising technique for patients with suspected renovascular disease and could be used as an alternative if gadolinium-based contrast agents cannot be administered. |
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Authors:
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Oliver K Mohrs; Steffen E Petersen; Thomas Schulze; Michael Zieschang; Harald Küx; Peter Schmitt; Sabine Bergemann; Hans-Ulrich Kauczor |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 195 ISSN: 1546-3141 ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-24 Completed Date: 2011-01-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
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Languages: eng Pagination: 1423-8 Citation Subset: AIM; IM |
Affiliation:
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University of Heidelberg, Department of Diagnostic and Interventional Radiology, Heidelberg, Germany. mohrs@radiologie-darmstadt.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Chi-Square Distribution Contrast Media / diagnostic use Electrocardiography* Female Humans Image Interpretation, Computer-Assisted Imaging, Three-Dimensional* Magnetic Resonance Angiography / methods* Magnetic Resonance Imaging Male Middle Aged Organometallic Compounds / diagnostic use Predictive Value of Tests Renal Artery Obstruction / diagnosis* Respiratory-Gated Imaging Techniques* Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Organometallic Compounds; 138071-82-6/gadobutrol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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