Document Detail

High levels of serum uric acid impair development of coronary collaterals in patients with acute coronary syndrome.
MedLine Citation:
PMID:  21948975     Owner:  NLM     Status:  MEDLINE    
We evaluated the association of serum uric acid (SUA) level and development of coronary collateral vessels (CCVs) in patients with acute coronary syndrome (ACS). Patients (n = 224) with ACS were included in the study. Coronary collateral vessels were graded according to the Rentrop scoring system. Rentrop grade 0 was accepted as absence of CCV (group 1; n = 117) and Rentrop grade ≥1 was accepted as presence of CCV (group 2; n = 107). Rentrop 0-1 (poor CCV) were determined in 167 patients and Rentrop 2-3 (good CCV) were determined in 57 patients. Both presence of CCV (P < .001) and development of good CCV (P = .003) were significantly associated with low levels of SUA. We suggest that high levels of SUA affect the CCV development negatively in nondiabetic and nonhypertensive patients with ACS.
Mustafa Duran; Ender Ornek; Sani N Murat; Murat Turfan; Mehmet A Vatankulu; Ayse Ocak; Cihan Doger; Ahmet A Yalcin; Muhammed B Demircelik
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2011-09-22
Journal Detail:
Title:  Angiology     Volume:  63     ISSN:  1940-1574     ISO Abbreviation:  Angiology     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-06-21     Completed Date:  2012-09-04     Revised Date:  2013-05-14    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  472-5     Citation Subset:  IM    
Department of Cardiology, Etlik Ihtisas Research and Education Hospital, Ankara, Turkey.
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MeSH Terms
Acute Coronary Syndrome / etiology*,  physiopathology,  radiography
Biological Markers / blood
Collateral Circulation*
Coronary Angiography
Coronary Circulation*
Disease Progression
Follow-Up Studies
Hyperuricemia / blood*,  complications
Middle Aged
Prospective Studies
Risk Factors
Uric Acid / blood*
Reg. No./Substance:
0/Biological Markers; 69-93-2/Uric Acid
Comment In:
Angiology. 2012 Aug;63(6):476-7; author reply 478-9   [PMID:  22718080 ]
Angiology. 2013 May;64(4):323-4   [PMID:  23553114 ]
Angiology. 2013 May;64(4):325-6   [PMID:  23553115 ]

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