| High Flow Extra-Intracranial Excimer Laser Assisted Non-Occlusive Anastomosis (ELANA) Bypass for Symptomatic Carotid Artery Occlusion. | |
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MedLine Citation:
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PMID: 21389885 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND:: A high flow bypass is theoretically more effective than a conventional low flow bypass in preventing strokes in patients with symptomatic carotid artery occlusion (CAO) and a compromised hemodynamic state of the brain. OBJECTIVE:: To study the results of Excimer Laser Assisted Non-occlusive Anastomosis (ELANA) high flow extra-intracranial (EC-IC) bypass surgery in these patients. METHODS:: Between August 1998 and May 2008, 24 patients underwent ELANA EC-IC bypass surgery because of transient ischemic attacks (TIAs) or minor ischemic stroke associated with CAO. We retrospectively collected information. Follow-up data were updated by structured telephone interviews between May and September 2008. RESULTS:: In all patients the ELANA EC-IC bypass was patent at the end of surgery with a mean flow of 106 (± 41) mL/min. Within 30 days after the operation, 22 patients (92%) had no major complications while two patients (8%) suffered from a fatal intracerebral hemorrhage. During follow-up of a mean 4.4 (± 2.4) years the bypass remained patent in 18 of the 22 surviving patients (82%) with a mean flow of 141 (± 59) mL/min. All patients with a patent bypass remained free of TIAs and ischemic stroke. In 4 patients the bypass occluded, accompanied by ipsilateral TIAs in 2 patients, ipsilateral ischemic stroke in 1 patient, and contralateral ischemic stroke in another patient. CONCLUSION:: ELANA EC-IC bypass surgery in patients with CAO is technically feasible and results in cessation of ongoing TIAs and minor ischemic strokes, but carries a risk of post-operative hemorrhage. |
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Authors:
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Tristan P C van Doormaal; Catharine J M Klijn; Perry T C van Doormaal; L Jaap Kappelle; Luca Regli; Cornelius A F Tulleken; Albert van der Zwan |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-3-08 |
Journal Detail:
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Title: Neurosurgery Volume: - ISSN: 1524-4040 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-3-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7802914 Medline TA: Neurosurgery Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Rudolf Magnus Institute of Neuroscience, 1Department of Neurosurgery, 2Department of Neurology, University Medical Center Utrecht, Utrecht, The Netherlands. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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