| High-definition colonoscopy detects colorectal polyps at a higher rate than standard white-light colonoscopy. | |
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MedLine Citation:
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PMID: 19932768 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND & AIMS: Adenoma detection rates might be improved through use of high-definition colonoscopy, which can detect subtle mucosal changes. We investigated whether the use of high-definition white-light (HDWL) colonoscopy resulted in a higher rate of adenoma detection than standard-definition white-light (SDWL) colonoscopy in a clinical practice setting. METHODS: This retrospective study included 2430 patients who underwent colonoscopies from September 2006 to December 2007; 1226 received SDWL colonoscopy and 1204 received HDWL colonoscopy. We analyzed data from consecutive screening, surveillance, and diagnostic colonoscopies, comparing adenoma and overall polyp detection between procedures. Potentially confounding variables were controlled using multivariable logistic regression analysis. RESULTS: The adenoma detection rate was higher among patients who underwent HDWL compared with SDWL colonoscopies (28.8% vs 24.3%; P = .012), as was the polyp detection rate (42.2% vs 37.8%; P = .026). These findings remained after adjustments for potentially confounding variables (P = .018 and .022, respectively). CONCLUSIONS: In a general clinical practice setting, HDWL colonoscopy resulted in a higher adenoma detection rate compared with SDWL colonoscopy. The use of SDWL colonoscopy could reduce the number of missed adenomas and the subsequent risk for colorectal cancer. |
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Authors:
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Anna M Buchner; Muhammad W Shahid; Michael G Heckman; Rebecca B McNeil; Patrick Cleveland; Kanwar R Gill; Anthony Schore; Marwan Ghabril; Massimo Raimondo; Seth A Gross; Michael B Wallace |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't Date: 2009-11-22 |
Journal Detail:
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Title: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Volume: 8 ISSN: 1542-7714 ISO Abbreviation: Clin. Gastroenterol. Hepatol. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-29 Completed Date: 2010-06-07 Revised Date: 2011-03-28 |
Medline Journal Info:
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Nlm Unique ID: 101160775 Medline TA: Clin Gastroenterol Hepatol Country: United States |
Other Details:
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Languages: eng Pagination: 364-70 Citation Subset: IM |
Copyright Information:
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Copyright 2010 AGA Institute. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida 32224, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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diagnosis* Adolescent Adult Aged Aged, 80 and over Colonoscopy / methods* Colorectal Neoplasms / diagnosis* Female Humans Intestinal Polyps / diagnosis* Male Middle Aged Retrospective Studies Sensitivity and Specificity Young Adult |
| Comments/Corrections | |
Comment In:
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Clin Gastroenterol Hepatol. 2010 Apr;8(4):318-21
[PMID:
20026427
]
Clin Gastroenterol Hepatol. 2010 Oct;8(10):903; author reply 904 [PMID: 20580943 ] |
Erratum In:
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Clin Gastroenterol Hepatol. 2011 Mar;9(3):280 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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