Document Detail

"Hibernating" myocardium: asleep or part dead?
MedLine Citation:
PMID:  8800135     Owner:  NLM     Status:  MEDLINE    
Chronic ischemic dysfunction of the left ventricle is commonly presumed to represent "hibernating" myocardium. The implication of this assumption is that with successful reperfusion, systolic function will improve. Several diagnostic techniques including dobutamine stress echocardiography have been used to detect "viable" myocardium in the setting of chronic left ventricular dysfunction. Predictive accuracies of 70% to 85% have been reported for identifying myocardium that recovers function. Recovery of function has been variable and often dependent on the severity of dysfunction. All current models have presumed that chronically dysfunctioning myocardium is "hibernating." Obviously, in the chronic setting, dysfunction may have many causes and include components of transmural and nontransmural infarction as well as hibernating myocardium. This review focuses on the independent role that nontransmural infarction may play in chronic dysfunction and suggests its impact on diagnostic techniques used to identify hibernating myocardium.
W F Armstrong
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Publication Detail:
Type:  Editorial; Review    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  28     ISSN:  0735-1097     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1996-10-18     Completed Date:  1996-10-18     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  530-5     Citation Subset:  AIM; IM    
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MeSH Terms
Coronary Disease
Dobutamine / diagnostic use
Heart / radionuclide imaging
Myocardial Contraction
Myocardial Infarction*
Myocardial Ischemia*
Myocardial Stunning*
Ventricular Dysfunction, Left*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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