| Heterotopic ossification in critical illness and cancer: a report of 2 cases. | |
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MedLine Citation:
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PMID: 12048667 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Heterotopic ossification is the abnormal development of bone tissue within periarticular soft tissue. We present 2 Turkish patients with malignant thoracic cancer who underwent extensive thoracic surgery and required prolonged postoperative chemical paralysis and cardiorespiratory support for respiratory complications. Both patients were found by the physiatrist to have multiple, extensive heterotopic ossifications. Clinical findings in both patients included joint swelling and severe limitation in range of motion (ROM) associated with pain. The diagnoses were confirmed radiographically. After an extended length of inpatient rehabilitation, both patients improved their cumulative FIM instrument motor scores by 23 and were discharged with a trained family member. Our findings suggested that heterotopic ossification should be suspected in patients presenting with decreased ROM, increased pain, and joint swelling after prolonged immobilization. Serum alkaline phosphatase might be used as an effective screening tool. |
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Authors:
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Ying Guo; Christopher R Collaco; Eduardo Bruera |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Archives of physical medicine and rehabilitation Volume: 83 ISSN: 0003-9993 ISO Abbreviation: Arch Phys Med Rehabil Publication Date: 2002 Jun |
Date Detail:
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Created Date: 2002-06-05 Completed Date: 2002-06-25 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 2985158R Medline TA: Arch Phys Med Rehabil Country: United States |
Other Details:
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Languages: eng Pagination: 855-9 Citation Subset: AIM; IM |
Copyright Information:
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Copyright 2002 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation |
Affiliation:
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Department of Symptom Control and Palliative Care, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. yguo@mdanderson.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Humans Immobilization / adverse effects* Intensive Care Units Male Middle Aged Neoplasms / complications, therapy* Neuromuscular Nondepolarizing Agents / adverse effects Ossification, Heterotopic / etiology*, radiography, rehabilitation Physical Therapy Modalities Range of Motion, Articular Vecuronium Bromide / adverse effects |
| Chemical | |
Reg. No./Substance:
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0/Neuromuscular Nondepolarizing Agents; 50700-72-6/Vecuronium Bromide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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