Document Detail

Heterotopic ossification after knee dislocation: the predictive value of the injury severity score.
MedLine Citation:
PMID:  12759638     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the relationship of multiple variables, including the Injury Severity Score (ISS), closed head injury (CHI), and timing and type of surgery to formation of motion-limiting heterotopic ossification (HO) following knee dislocation. DESIGN: Longitudinal observational study. SETTING: University level 1 trauma center. PATIENTS/PARTICIPANTS: Thirty-five consecutive patients with 36 knee dislocations (OTA fracture and dislocation classification 40-D) admitted over a 26-month period. MAIN OUTCOME MEASUREMENTS: Admission ISS, Glasgow Coma scale (GCS) scores, CHI, timing (> or < 3 weeks from injury) and type (open or arthroscopic) of surgery, number of cruciate ligaments reconstructed, medial surgical procedure, and eventual presence or absence of motion-limiting HO. RESULTS: A classification system for HO was developed ranging from none (type 0) to ankylosing (type IV) HO. Twenty-nine patients with type 0-III HO recovered an average range of motion of 126 degrees at an average of 14 months (group A). Six patients formed ankylosing type IV HO (group B). The ISS in group A ranged from 9 to 26. ISS in group B ranged from 26 to 50 (P < 0.001). Regarding the formation of type IV HO, the sensitivity of an ISS >/=26 was 100%, the specificity was 97%, and the positive predictive value was 86%. Patients in group B had a greater incidence of documented CHI (P < 0.025). Timing and type of surgery, number of ligaments reconstructed, and whether or not the patient had a medial surgical procedure had no statistical influence on degree of HO formation. CONCLUSIONS: An ISS of 26 seems to be a discrete boundary above which patients with knee dislocation are at extremely high risk for type IV HO formation if undergoing surgical reconstruction and below which patients are likely spared this complication. The presence of a CHI is a significant factor in type IV HO formation, although harder to quantify. None of the remaining independent variables studied were significantly related to ankylosing type IV HO formation.
William J Mills; Nirmal Tejwani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of orthopaedic trauma     Volume:  17     ISSN:  0890-5339     ISO Abbreviation:  J Orthop Trauma     Publication Date:  2003 May 
Date Detail:
Created Date:  2003-05-21     Completed Date:  2003-08-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8807705     Medline TA:  J Orthop Trauma     Country:  United States    
Other Details:
Languages:  eng     Pagination:  338-45     Citation Subset:  IM    
Department of Orthopaedics, University of Washington, Harborview Medical Center, Seattle, Washington, USA.
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MeSH Terms
Anterior Cruciate Ligament / injuries
Glasgow Coma Scale
Head Injuries, Closed / complications
Injury Severity Score*
Knee Dislocation / complications*,  epidemiology,  pathology,  surgery
Knee Joint / pathology,  physiopathology
Medial Collateral Ligament, Knee / injuries
Ossification, Heterotopic / classification,  etiology*,  physiopathology,  radiography
Posterior Cruciate Ligament / injuries
Range of Motion, Articular

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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