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Heterotopic ossification as a complication of carbon monoxide intoxication.
MedLine Citation:
PMID:  20714963     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
PURPOSE: Gait impairment due to encephalopathy and neuropathy has been reported in carbon monoxide (CO) intoxication. Heterotopic ossification (HO) as a cause of gait impairment after CO intoxication has never been reported. In this study we report a patient with HO after CO intoxication. CASE REPORT: A 21 year-old woman developed HO after CO intoxication, which resulted in progressive difficulties in ambulation. Bone scan 3 months later revealed HO around bilateral femoral joints and extended to proximal thighs. Selective involvement of bilateral iliopsoas, tensor fascia lata, rectus femoris, sartorius, and quadriceps muscles were found by muscle magnetic resonance imaging. Surgical intervention improved ambulation. A repeated bone scan 6 months after the operation showed no focal recurrence. CONCLUSION: CO intoxication can lead to HO through ischemic reperfusion injury. HO should be considered in patients with ambulation difficulties after CO intoxication. Excision of HO may be a treatment option to correct limitations in locomotion.
Authors:
Sheng-Hang Chen; Shu-Hua Huang; Wen-Neng Chang; Chun-Chung Lui; Chi-Wei Huang; Yu-Ting Lin; Chiung-Chih Chang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurologica Taiwanica     Volume:  19     ISSN:  1028-768X     ISO Abbreviation:  Acta Neurol Taiwan     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-08-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815355     Medline TA:  Acta Neurol Taiwan     Country:  China (Republic : 1949- )    
Other Details:
Languages:  eng     Pagination:  120-4     Citation Subset:  IM    
Affiliation:
Department of Neurology, Chang Gung Memorial Hospital-Kaohsiung Medical Center and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
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