| Heterogeneous tissue in the thyroid fossa on ultrasound in infants with proven thyroid ectopia on isotope scan--a diagnostic trap. | |
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MedLine Citation:
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PMID: 20066409 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Thyroid imaging is of proven help in establishing a diagnosis of congenital hypothyroidism in infants. US often shows tissue in the thyroid fossa when radionuclide scintigraphy reveals only ectopic uptake. OBJECTIVE: Our hypothesis was that the use of US alone could lead to the mistaken diagnosis of normal or dysplastic thyroid in cases of scintigraphy-proven thyroid ectopia. MATERIALS AND METHODS: We undertook a detailed retrospective review and analysis of imaging and concurrent biochemistry in infants with thyroid ectopia, confirmed by radionuclide scintigraphy. RESULTS: Eighteen infants had thyroid ectopia; ten of the original US reports had suggested that cervical thyroid tissue was present. Review showed bilateral tissue in the thyroid fossa in all that was non-thyroidal in nature since, apart from showing no radionuclide uptake, it exhibited some or all of the following typical features: hyperechogenicity, heterogeneity, small size, poor vascularity, and anechoic and/or hypoechoic cysts. Also, extension of the tissue both around and behind the large cervical blood vessels was a universal finding. CONCLUSION: Considerable experience is required to interpret neonatal thyroid US. We caution against diagnosing a dysplastic/hypoplastic thyroid gland in situ on the basis of US alone, particularly if the tissue exhibits any of the non-thyroidal features described. |
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Authors:
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Jeremy H Jones; Morag Attaie; Sanjay Maroo; David Neumann; Rebecca Perry; Malcolm D C Donaldson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-01-12 |
Journal Detail:
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Title: Pediatric radiology Volume: 40 ISSN: 1432-1998 ISO Abbreviation: Pediatr Radiol Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-03-30 Completed Date: 2010-06-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0365332 Medline TA: Pediatr Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 725-31 Citation Subset: IM |
Affiliation:
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Department of Child Health, Royal Hospital for Sick Children, Dalnair Street, Yorkhill, Glasgow, Lanarkshire, G3 8SJ, UK. jhj1c@clinmed.gla.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Choristoma
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radionuclide imaging*,
ultrasonography* Diagnostic Errors / prevention & control* Female Humans Infant, Newborn Male Reproducibility of Results Sensitivity and Specificity Thyroid Gland / radionuclide imaging*, ultrasonography* Tongue Diseases / radionuclide imaging*, ultrasonography* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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