Document Detail


Heterogeneous cardiac proteasomes: mandated by diverse substrates?
MedLine Citation:
PMID:  21487029     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Proteasome biology has taken central stage in cardiac physiology and pathophysiology. The molecular heterogeneity of proteasome subpopulations supports the specificity of proteasome function to degrade diverse substrate repertoires. Unveiling the dynamics of proteasome function should inspire new therapeutic strategies for combating cardiac disease.
Authors:
Sarah B Scruggs; Peipei Ping; Chenggong Zong
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physiology (Bethesda, Md.)     Volume:  26     ISSN:  1548-9221     ISO Abbreviation:  Physiology (Bethesda)     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-04-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101208185     Medline TA:  Physiology (Bethesda)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  106-14     Citation Subset:  IM    
Affiliation:
Departments of Physiology and Medicine, Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, California.
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