Document Detail


Heterogeneity of serum basal C peptide levels amongst Arab patients with diabetes mellitus.
MedLine Citation:
PMID:  3149222     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thirty-four Arab patients with history of diabetes mellitus but without history of ketoacidosis (Group 2), and 16 Arab patients with history of diabetes mellitus and ketoacidosis (Group 1) were studied. They were compared with 15 healthy control subjects and were further broken down according to sex and type of therapy. Fasting serum C-peptide, glucose and glycosylated haemoglobin levels were measured in all subjects. C-peptide levels in Group 2 were higher (t = 2.95) and exhibited greater heterogeneity (Variance ratio 3.60, p less than 0.005) than those in Group 1. Female subjects in Group 2 were more obese than male subjects in the same group, and exhibited greater heterogeneity of their C-peptide levels (Variance ratio 9.47, p less than 0.001). Although male patients in Group 2 on insulin therapy were older than male subjects on diet or oral hypoglycemic agents (t = 3.52, p less than 0.01), female subjects on insulin therapy were younger than those on diet or oral hypoglycemic agents (t = 2.05, p less than 0.05). Furthermore female patients on insulin therapy had lower serum glycosylated haemoglobin levels than female subjects on oral hypoglycemic agents (t = 2.05, p less than 0.05) but male patients on insulin therapy had higher serum glycosylated haemoglobin than those on oral hypoglycemic agents. These data suggest the earlier tendency of physicians to prescribe insulin in women of child bearing age but suggest that earlier prescribing habits of insulin may improve diabetic control.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
N Abdella; W Luqman; M Hassan; A Salman
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Diabetes research (Edinburgh, Scotland)     Volume:  9     ISSN:  0265-5985     ISO Abbreviation:  Diabetes Res.     Publication Date:  1988 Sep 
Date Detail:
Created Date:  1989-05-18     Completed Date:  1989-05-18     Revised Date:  2007-09-11    
Medline Journal Info:
Nlm Unique ID:  8502339     Medline TA:  Diabetes Res     Country:  SCOTLAND    
Other Details:
Languages:  eng     Pagination:  47-50     Citation Subset:  IM    
Affiliation:
Department of Medicine, Faculty of Medicine, Kuwait University.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Blood Glucose / analysis
C-Peptide / blood*
Diabetes Mellitus, Type 1 / blood*
Diabetes Mellitus, Type 2 / blood*
Diabetic Ketoacidosis / blood*
Female
Hemoglobin A, Glycosylated / analysis
Humans
Kuwait
Male
Sex Factors
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/C-Peptide; 0/Hemoglobin A, Glycosylated

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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