Document Detail

Heterogeneity of metabolic response to muscular exercise in humans. New criteria of invariance defined by in vivo phosphorus-31 NMR spectroscopy.
MedLine Citation:
PMID:  2226826     Owner:  NLM     Status:  MEDLINE    
31P NMR spectroscopy at 4.7 T has been used in vivo to follow metabolic changes associated with exercise and subsequent recovery in the forearm flexor digitorum superficialis muscle of 14 healthy volunteers. The muscle content in phosphomonoesters at rest provides an index of glycogenolytic activity. Quantitative linear correlations have been shown to link end-of-exercise acidosis to recovery kinetics of phosphocreatine and phosphocreatine/organic phosphate ratio. These linear relationships constitute new metabolic invariants to be used in the study of myopathies and muscle adaptation to exercise.
D Bendahan; S Confort-Gouny; G Kozak-Reiss; P J Cozzone
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  FEBS letters     Volume:  272     ISSN:  0014-5793     ISO Abbreviation:  FEBS Lett.     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1990-12-13     Completed Date:  1990-12-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0155157     Medline TA:  FEBS Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  155-8     Citation Subset:  IM; S    
Centre de Résonance Magnétique Biologique et Médicale, Faculté de Médecine de Marseille, France.
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MeSH Terms
Adenosine Triphosphate / metabolism
Esters / metabolism
Exercise / physiology*
Hydrogen-Ion Concentration
Magnetic Resonance Spectroscopy*
Muscles / metabolism*
Organophosphorus Compounds / metabolism
Phosphates / metabolism
Phosphocreatine / metabolism
Reg. No./Substance:
0/Esters; 0/Organophosphorus Compounds; 0/Phosphates; 56-65-5/Adenosine Triphosphate; 67-07-2/Phosphocreatine

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