| Heterogeneity in the distal nephron of the salamander (Ambystoma tigrinum): a correlated structure function study of isolated tubule segments. | |
| | |
MedLine Citation:
|
PMID: 7149280 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Studies on isolated perfused tubules of the tiger salamander (Ambystoma tigrinum) have shown that the distal nephron is heterogeneous with respect to function (Stoner, 1977). In this study, the initial portion of the distal tubule (diluting segment) exhibited a voltage, positive in the lumen, and a net absorption of chloride. Since the chloride was transported against an electro-chemical gradient, its transport was active. More distad, the junctional segment exhibited a lumen-negative voltage and sodium, rather than chloride, was transported actively. More recently Delaney and Stoner (1981) have demonstrated in vitro that the collecting duct of this species also has a lumen-negative voltage which is probably associated with active sodium reabsorption. The primary objective of the present paper was to correlate the morphology of the diluting and junctional segments of the Ambystoma distal tubules with the physiologic data from the same isolated perfused tubules. The results indicate that the morphological heterogeneity previously demonstrated in distal tubules of Necturus exists with respect to both structure and function in Ambystoma. The cell types found in the amphibian distal nephron appear to be homologous to those seen in the mammalian nephron. |
| | |
Authors:
|
D E Hinton; L C Stoner; M Burg; B F Trump |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Anatomical record Volume: 204 ISSN: 0003-276X ISO Abbreviation: Anat. Rec. Publication Date: 1982 Sep |
Date Detail:
|
Created Date: 1983-01-19 Completed Date: 1983-01-19 Revised Date: 2003-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 0370540 Medline TA: Anat Rec Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 21-32 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Kidney Tubules / anatomy & histology*, physiology, ultrastructure Microscopy, Electron Nephrons / anatomy & histology*, physiology, ultrastructure Perfusion Urodela / anatomy & histology*, physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cell flux through S phase in the mouse duodenal epithelium determined by cell sorting and radioautog...
Next Document: Light microscopic morphometric analysis of rat ileal mucosa: II. Component quantitation of Paneth ce...