Document Detail

Heterogeneity of human chromosome 9 constitutive heterochromatin as revealed by sequential distamycin A/DAPI staining and C-banding.
MedLine Citation:
PMID:  6167506     Owner:  NLM     Status:  MEDLINE    
Distamycin A/DAPI staining and sequential C-banding of human lymphocyte chromosomes reveals the regular occurrence of differentially staining subfractions of chromosome 9 constitutive heterochromatin. These subfractions are regionally organized as two subsegments: a distal one, which fluoresces brightly with DAPI after preincubation with distamycin A and a proximal one, which stains intensely with Giemsa after sequential C-banding. Observations are presented that indicate an occasionally independent genetic behavior of these heterochromatin subfractions.
C H Buys; W L Gouw; J A Blenkers; C H van Dalen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human genetics     Volume:  57     ISSN:  0340-6717     ISO Abbreviation:  Hum. Genet.     Publication Date:  1981  
Date Detail:
Created Date:  1981-10-28     Completed Date:  1981-10-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7613873     Medline TA:  Hum Genet     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  28-30     Citation Subset:  IM    
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MeSH Terms
Amidines / diagnostic use
Chromosome Banding
Chromosomes, Human, 6-12 and X / ultrastructure*
Distamycins / diagnostic use
Fluorescent Dyes
Heterochromatin / ultrastructure*
Indoles / diagnostic use
Lymphocytes / cytology
Staining and Labeling
Reg. No./Substance:
0/Amidines; 0/Distamycins; 0/Fluorescent Dyes; 0/Heterochromatin; 0/Indoles; 47165-04-8/DAPI

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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