Document Detail

Heterogeneity of cognitive profiles in normal aging: implications for early manifestations of Alzheimer's disease.
MedLine Citation:
PMID:  7650100     Owner:  NLM     Status:  MEDLINE    
This study explores the presence of homogeneous subgroups among 156 normal elderly subjects based on their performance on a battery of neuropsychological tests. Subjects ranged in age between 57 and 85 years and included 62 males and 94 females with a mean age 70.7 years, mean education 14.1 years, and mean Full Scale IQ of 117.2. Six clusters were extracted, three of which are likely to represent preclinical stages of the dementing process with distinct patterns of cognitive deficits. The results are discussed in light of different models of cognitive deterioration in DAT.
M Mitrushina; C Uchiyama; P Satz
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical and experimental neuropsychology     Volume:  17     ISSN:  1380-3395     ISO Abbreviation:  J Clin Exp Neuropsychol     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-09-28     Completed Date:  1995-09-28     Revised Date:  2008-04-14    
Medline Journal Info:
Nlm Unique ID:  8502170     Medline TA:  J Clin Exp Neuropsychol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  374-82     Citation Subset:  IM    
UCLA School of Medicine 90024-1759, USA.
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MeSH Terms
Aged, 80 and over
Alzheimer Disease / classification,  diagnosis*,  psychology
Cognition Disorders / classification,  diagnosis*,  psychology
Diagnosis, Differential
Geriatric Assessment*
Middle Aged
Neuropsychological Tests* / statistics & numerical data
Reference Values

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