Document Detail


Heterogeneity of Müller cell endfeet in the rabbit retina as revealed by freeze-fracturing.
MedLine Citation:
PMID:  3696499     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The Müller cell membranes of the rabbit retina were investigated by means of freeze-fracturing. Orthogonal arrays of particles (OAP) were found almost exclusively where the Müller cell endfoot had direct contact with the vitreous body. In the center of the retina where the Müller cells are long and thin, the density of OAP was about 170/microns2. In the periphery where the Müller cells are shorter and thicker, the density of OAP was about 20/microns2. In this area, only half of the Müller cell endfeet were equipped with OAP. The results are discussed with respect to electrophysiological studies on the role of various K+ channels in glial cells. It is proposed that OAP might possibly represent specialized 'maxi'-K+ channels which are involved in K+ spatial buffering of the extracellular space.
Authors:
H Wolburg; K Berg
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuroscience letters     Volume:  82     ISSN:  0304-3940     ISO Abbreviation:  Neurosci. Lett.     Publication Date:  1987 Dec 
Date Detail:
Created Date:  1988-01-28     Completed Date:  1988-01-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7600130     Medline TA:  Neurosci Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  273-7     Citation Subset:  IM    
Affiliation:
Pathologisches Institut, Universität Tübingen, F.R.G.
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MeSH Terms
Descriptor/Qualifier:
Animals
Freeze Fracturing
Rabbits
Retina / cytology*,  ultrastructure

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