Document Detail


Herpes zoster-associated voiding dysfunction in hematopoietic malignancy patients.
MedLine Citation:
PMID:  18173598     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Voiding dysfunction is a rare but important complication of lumbo-sacral herpes zoster. Although the symptoms are transient, the clinical impact on immunocompromised patients cannot be overlooked. METHODS: To clarify the time course of voiding dysfunction in herpes zoster, 13 herpes zoster patients with voiding dysfunction were retrospectively analyzed. RESULTS: Of 13 patients, 12 had background disease, and six of these were hematopoietic malignancies; four of these patients were hematopoietic stem cell transplant (HSCT) recipients. Ten patients had sacral lesions, two had lumbar, and one had thoracic lesions. Interestingly, patients with severe rash, or with hematopoietic malignancy had later onset of urinary retention than did patients with mild skin symptoms (Mann-Whitney U analysis, P = 0.053) or with other background disease (P = 0.0082). Patients with severe skin rash also had longer durations (P = 0.035). In one case, acute urinary retention occurred as late as 19 days after the onset of skin rash. CONCLUSIONS: In immune compromised subjects, attention should be paid to patients with herpes zoster in the lumbo-sacral area for late onset of acute urinary retention even after the resolution of skin symptoms.
Authors:
Shinichi Imafuku; Masakazu Takahara; Takeshi Uenotsuchi; Koji Iwato; Masutaka Furue
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of dermatology     Volume:  47     ISSN:  1365-4632     ISO Abbreviation:  Int. J. Dermatol.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2008-01-04     Completed Date:  2008-04-07     Revised Date:  2009-03-05    
Medline Journal Info:
Nlm Unique ID:  0243704     Medline TA:  Int J Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  36-9     Citation Subset:  IM    
Affiliation:
Division of Dermatology and Hematology, Hiroshima Red Cross and Atomic Bomb Survivor's Hospital, and Department of Dermatology, Graduate School of Medical Sciences, Kyushu University. dermatologist@mac.com
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MeSH Terms
Descriptor/Qualifier:
Acyclovir / administration & dosage
Adult
Aged
Aged, 80 and over
Antiviral Agents / administration & dosage
Dysuria / etiology*
Female
Hematologic Neoplasms / complications
Herpes Zoster / complications*,  drug therapy,  immunology
Humans
Immunocompromised Host
Lumbosacral Region / pathology
Male
Middle Aged
Retrospective Studies
Urinary Catheterization
Urinary Retention / etiology*
Chemical
Reg. No./Substance:
0/Antiviral Agents; 59277-89-3/Acyclovir

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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