Document Detail

Heroin-related deaths: new epidemiologic insights.
MedLine Citation:
PMID:  6474188     Owner:  NLM     Status:  MEDLINE    
Deaths associated with injected street preparations of heroin increased substantially in the District of Columbia between April 1979 and December 1982. The 1981 population-based mortality rate (17.4 per 100,000) is possibly the highest ever reported. A case-control study based on toxicologic analyses of postmortem blood samples indicates that concentrations of both heroin and ethanol are substantial risk factors for heroin-related deaths. Analyses of the composition of street-level preparations of heroin and quarterly mortality indicate that the quantity of heroin in packages sold on the street, the price of heroin in these packages, and the quinine weight per package each predict deaths equally as well. An increase in the causal use of heroin in combination with ethanol and quinine is the probable cause of this epidemic.
A J Ruttenber; J L Luke
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Science (New York, N.Y.)     Volume:  226     ISSN:  0036-8075     ISO Abbreviation:  Science     Publication Date:  1984 Oct 
Date Detail:
Created Date:  1984-10-25     Completed Date:  1984-10-25     Revised Date:  2007-03-19    
Medline Journal Info:
Nlm Unique ID:  0404511     Medline TA:  Science     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  14-20     Citation Subset:  IM    
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MeSH Terms
Alcoholic Intoxication / complications
Costs and Cost Analysis
District of Columbia
Drug Contamination
Ethanol / blood
Heroin / analysis,  poisoning*
Morphine / blood
Pharmaceutical Preparations*
Quinine / poisoning
Street Drugs*
Substance-Related Disorders / complications,  mortality*
Reg. No./Substance:
0/Pharmaceutical Preparations; 0/Street Drugs; 130-95-0/Quinine; 561-27-3/Heroin; 57-27-2/Morphine; 64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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