Document Detail


Heroin-associated nephropathy.
MedLine Citation:
PMID:  15709895     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Since the first reports in the late 1960s and early 1970s there have been numerous studies describing the clinical and pathological features of renal diseases associated with chronic parenteral abuse of heroin, cocaine, morphine, amphetamine, and other narcotic and hallucinogenic drugs, including several adulterants. The past 35 years have witnessed an explosive growth in illicit drug use in many parts of the world. Meanwhile, drug addict nephropathy constitutes an important cause of end-stage renal disease. The term heroin-associated nephropathy' includes different morphological findings following chronic drug abuse. Up to now it still remains ambiguous as to whether or not heroin/morphine itself, adulterants, other diseases like hepatitis B and C infection, or HIV, lead to a spectrum of morphologically described heroin-associated' findings in the kidneys. As a measure of prevention it appears that the purity of heroin plays an important role.
Authors:
Reinhard B Dettmeyer; Johanna Preuss; Heike Wollersen; Burkhard Madea
Related Documents :
19038525 - A pilot study of community-friendly manual-guided drug counseling.
10821445 - Long-term oscillation of corticosterone following intermittent cocaine.
9668685 - Medication development of ibogaine as a pharmacotherapy for drug dependence.
17175125 - Factors influencing the contamination of uk banknotes with drugs of abuse.
12472725 - Mathematical modelling of antifungal action.
11703845 - The phenomenon of treatment failures in human african trypanosomiasis.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Expert opinion on drug safety     Volume:  4     ISSN:  1744-764X     ISO Abbreviation:  Expert Opin Drug Saf     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-02-15     Completed Date:  2006-02-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101163027     Medline TA:  Expert Opin Drug Saf     Country:  England    
Other Details:
Languages:  eng     Pagination:  19-28     Citation Subset:  IM    
Affiliation:
University of Bonn, Department of Forensic Medicine, Stiftsplatz 12, D-53111, Bonn, Germany. rdettmey@uni-bonn.de.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
HIV Infections / complications
Hepatitis B, Chronic / complications,  etiology
Hepatitis C, Chronic / complications,  etiology
Heroin / adverse effects*,  chemistry
Heroin Dependence / complications
Humans
Kidney Diseases / chemically induced*,  physiopathology*
Narcotics / adverse effects*,  chemistry
Chemical
Reg. No./Substance:
0/Narcotics; 561-27-3/Heroin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Drug interactions with angiotensin receptor blockers.
Next Document:  Cardiovascular complications of immunosuppressive agents in renal transplant recipients.