Document Detail


Heritability of erythrocyte Na+-Li+ countertransport in relation to essential hypertension.
MedLine Citation:
PMID:  6329557     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The Na+-Li+ countertransport system in erythrocytes was investigated in patients with essential hypertension and control subjects. Furthermore, studies on the pairs of parent-offspring and husband-wife were added in order to evaluate heritability of the countertransport. The Na+-Li+ countertransport of patients with essential hypertension and normotensive subjects with the family history of hypertension was significantly increased in comparison with that of normotensive subjects without the family history. The correlation coefficient of the countertransport in pairs of parent-offspring was significant but not between husband-wife. These results support the concept of a genetic determinant for the countertransport system.
Authors:
S Kagamimori; M Takata; Y Naruse; M Watanabe; N Miyamoto; A Okada
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical and experimental hypertension. Part A, Theory and practice     Volume:  6     ISSN:  0730-0077     ISO Abbreviation:  Clin Exp Hypertens A     Publication Date:  1984  
Date Detail:
Created Date:  1984-08-03     Completed Date:  1984-08-03     Revised Date:  2008-02-12    
Medline Journal Info:
Nlm Unique ID:  8207790     Medline TA:  Clin Exp Hypertens A     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  951-60     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Biological Transport
Blood Pressure
Erythrocytes / metabolism*
Female
Humans
Hypertension / blood,  genetics*
Ion Channels / metabolism
Lithium / blood*
Male
Middle Aged
Sodium / blood*
Chemical
Reg. No./Substance:
0/Ion Channels; 7439-93-2/Lithium; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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