Document Detail

Heritability of blood pressure in 7- to 12-year-old Chinese twins, with special reference to body size effects.
MedLine Citation:
PMID:  2292369     Owner:  NLM     Status:  MEDLINE    
Systolic and diastolic blood pressures and body-size indices such as body height, body weight, sitting height, chest circumference, skinfold thickness, and body mass index (BMI) were assessed in 110 pairs of like-sex Chinese twins (75 monozygotic and 35 dizygotic) aged 7-12 years. Significant correlations of blood pressure with body-size indices were found. Prior to adjusting for body-size effects, three twin methods yielded low heritability estimates for both systolic (0.32-0.41) and diastolic (0.32-0.51) pressures. Adjusting systolic pressure for body height and BMI via multiple regression nearly halved heritability estimates, but adjusting diastolic pressure for body height and skinfold thickness only changed the estimates slightly.
Z Q Wang; Z Ouyang; D M Wang; X L Tang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Genetic epidemiology     Volume:  7     ISSN:  0741-0395     ISO Abbreviation:  Genet. Epidemiol.     Publication Date:  1990  
Date Detail:
Created Date:  1991-04-10     Completed Date:  1991-04-10     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8411723     Medline TA:  Genet Epidemiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  447-52     Citation Subset:  IM    
School of Public Health, Harbin Medical University, China.
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MeSH Terms
Blood Pressure / genetics*,  physiology
Body Constitution / physiology
Genetic Variation
Statistics as Topic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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