Document Detail


Heritability of blood pressure in 7- to 12-year-old Chinese twins, with special reference to body size effects.
MedLine Citation:
PMID:  2292369     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Systolic and diastolic blood pressures and body-size indices such as body height, body weight, sitting height, chest circumference, skinfold thickness, and body mass index (BMI) were assessed in 110 pairs of like-sex Chinese twins (75 monozygotic and 35 dizygotic) aged 7-12 years. Significant correlations of blood pressure with body-size indices were found. Prior to adjusting for body-size effects, three twin methods yielded low heritability estimates for both systolic (0.32-0.41) and diastolic (0.32-0.51) pressures. Adjusting systolic pressure for body height and BMI via multiple regression nearly halved heritability estimates, but adjusting diastolic pressure for body height and skinfold thickness only changed the estimates slightly.
Authors:
Z Q Wang; Z Ouyang; D M Wang; X L Tang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Genetic epidemiology     Volume:  7     ISSN:  0741-0395     ISO Abbreviation:  Genet. Epidemiol.     Publication Date:  1990  
Date Detail:
Created Date:  1991-04-10     Completed Date:  1991-04-10     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8411723     Medline TA:  Genet Epidemiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  447-52     Citation Subset:  IM    
Affiliation:
School of Public Health, Harbin Medical University, China.
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MeSH Terms
Descriptor/Qualifier:
Blood Pressure / genetics*,  physiology
Body Constitution / physiology
Child
China
Genetic Variation
Humans
Statistics as Topic
Twins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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