Document Detail


Heredity and changes in hormones and metabolic rates with short-term training.
MedLine Citation:
PMID:  3521318     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this experiment was to assess the effects of a 22-day training program on resting metabolic rate (RMR), thermic effect of a meal (TEM), and associated hormonal changes. Six pairs of male monozygotic twins were submitted to a 22-day ergocycle exercise program designed to induce a deficit in energy balance of 4.2 MJ per day. RMR and TEM after a 4.2-MJ meal challenge were measured before and after training. Results indicated that RMR and TEM did not change significantly, although a large variation in response between twin pairs was observed. Moreover, training reduced (P less than 0.05) basal and postprandial insulin response, plasma thyroid hormones triiodothyronine (T3), thyroxine (T4), and FT4 (P less than 0.05). Absolute changes in RMR and TEM exhibited significant within-pair resemblance in response, with intraclass correlations reaching r = 0.81 (P less than 0.05) and r = 0.72 (P less than 0.05), respectively. Changes in T4 and FT4 also exhibited moderate within-pair resemblance (0.42 less than or equal to r less than or equal to 0.71). These results suggest that short-term exercise training does not modify RMR and TEM but can significantly decrease plasma levels of insulin and thyroid hormones. Moreover, the similarity of response within twin pairs suggests that heredity plays a role in determining RMR, TEM, and thyroid hormone adaptation to exercise training generating a negative energy balance.
Authors:
E T Poehlman; A Tremblay; A Nadeau; J Dussault; G Thériault; C Bouchard
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of physiology     Volume:  250     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1986 Jun 
Date Detail:
Created Date:  1986-07-23     Completed Date:  1986-07-23     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  E711-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Basal Metabolism*
Blood Glucose / metabolism
Body Temperature Regulation
Energy Metabolism
Food
Genetics*
Humans
Insulin / metabolism*
Male
Norepinephrine / blood
Oxygen Consumption
Physical Exertion*
Thyroid Hormones / blood*
Thyroxine / blood
Triiodothyronine / blood
Triiodothyronine, Reverse / blood
Twins, Monozygotic
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Thyroid Hormones; 11061-68-0/Insulin; 51-41-2/Norepinephrine; 5817-39-0/Triiodothyronine, Reverse; 6893-02-3/Triiodothyronine; 7488-70-2/Thyroxine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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