| Hereditary vacuolar internal anal sphincter myopathy causing proctalgia fugax and constipation: a new case contribution. | |
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MedLine Citation:
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PMID: 15716662 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hereditary anal sphincter myopathy is rare. We present a family with one affected member with proctalgia fugax, constipation and internal anal sphincter hypertrophy. Ultrastructural findings show vacuolization of smooth muscle cells without the characteristic polyglucosan inclusion. Further relief of symptoms was obtained using an oral calcium antagonist. Based on clinical presentation, endosonography and morphological findings, we consider our case is a histological variant of the vacuolar myopathy originally described. |
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Authors:
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Fernando de la Portilla; Juan José Borrero; Enrique Rafel |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: European journal of gastroenterology & hepatology Volume: 17 ISSN: 0954-691X ISO Abbreviation: Eur J Gastroenterol Hepatol Publication Date: 2005 Mar |
Date Detail:
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Created Date: 2005-02-17 Completed Date: 2005-06-06 Revised Date: 2009-10-16 |
Medline Journal Info:
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Nlm Unique ID: 9000874 Medline TA: Eur J Gastroenterol Hepatol Country: England |
Other Details:
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Languages: eng Pagination: 359-61 Citation Subset: IM |
Affiliation:
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Coloproctology Unit, Department of General Surgery, Hospital Juan Ramón Jiménez, Huelva, Spain. delaportilla@ya.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Anus Diseases / complications, genetics*, pathology Calcium Channel Blockers / therapeutic use Constipation / etiology*, pathology Female Humans Hypertrophy Muscle, Smooth / pathology Muscular Diseases / complications, genetics*, pathology Nifedipine / therapeutic use Pain / etiology, pathology Rectal Diseases / etiology, pathology Treatment Outcome Vacuoles / pathology |
| Chemical | |
Reg. No./Substance:
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0/Calcium Channel Blockers; 21829-25-4/Nifedipine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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