Document Detail


Hereditary sensory neuropathy with deafness and dementia: a clinical and neuroimaging study.
MedLine Citation:
PMID:  10210919     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe three sibling patients with autosomal dominantly inherited sensory neuropathy, sensorineural hearing loss and dementia. The features of cognitive-behavioral deficits in the patients, including executive dysfunction, apathy, indifference and inattention, were consistent with a frontal lobe dysfunction. Magnetic resonance imaging showed a diffuse brain atrophy. A fluorodeoxyglucose positron emission tomography in one patient and a single photon emission computed tomography in another demonstrated a glucose hypometabolism or a hypoperfusion in the medial frontal and thalamic regions. Primary frontal involvement or frontal dysfunction secondary to thalamic lesions may contribute to the nature of dementia in these patients.
Authors:
K Hojo; T Imamura; M Takanashi; K Ishii; M Sasaki; S Imura; R Ozono; Y Takatsuki; S Takauchi; E Mori
Related Documents :
9532279 - Evaluation of selection criteria used in alzheimer's disease clinical trials.
20972149 - Pomd01 blinded analysis of conventional mri in a cohort of pathologically confirmed par...
24001399 - Dynamic behaviour of selected pet tracers in embryonated chicken eggs.
14707319 - Hippocampal mri volumetry in cognitively discordant monozygotic twin pairs.
18488889 - Classifying late-onset dementia with mri: is arteriosclerotic brain degeneration the mo...
16092099 - Atypical parkinsonism of japan: amyotrophic lateral sclerosis-parkinsonism-dementia com...
16628439 - The accuracy of mri in diagnosis of suspected deep vein thrombosis: systematic review a...
7502969 - White matter changes caused by chronic solvent abuse.
15295399 - Postpartum cerebral angiopathy: an important diagnostic consideration in the postpartum...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of neurology : the official journal of the European Federation of Neurological Societies     Volume:  6     ISSN:  1351-5101     ISO Abbreviation:  Eur. J. Neurol.     Publication Date:  1999 May 
Date Detail:
Created Date:  2000-06-26     Completed Date:  2000-06-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9506311     Medline TA:  Eur J Neurol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  357-61     Citation Subset:  IM    
Copyright Information:
Copyright 1999 Lippincott Williams & Wilkins
Affiliation:
Division of Clinical Neurosciences, Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Deafness / complications*,  genetics,  pathology*
Dementia / complications*,  genetics,  pathology*
Female
Frontal Lobe / pathology,  radionuclide imaging
Hereditary Sensory and Autonomic Neuropathies / complications*,  genetics,  pathology*
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Pedigree
Thalamus / pathology,  radionuclide imaging
Tomography, Emission-Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Linguistic impairment after right cerebellar stroke: a case report.
Next Document:  Bilateral sphenoid wing metastases of prostate cancer presenting with extensive brain edema.