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Hereditary premature sensescence of the rabbit. I. Chronic form; general features.
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MedLine Citation:
PMID:  13733754     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The occurrence of hereditary premature senescence in a family of pure bred Belgian hares belonging to a rabbit-breeding colony organized for the investigation of constitutional problems, has been described. Representatives of 20 generations of the complex have been studied. The condition was a degeneration of variable degrees of severity and two principal forms were recognized, the acute and the chronic, the chronic being the more frequent. The chronic form has now been described in terms of the principal local or external manifestations; that is, degeneration of the coat and skin, lesions of the eyes and feet, and reproductive abnormalities, and of the general deterioration which in severe cases pursued a progressive course characterized by muscle wasting, fat reduction, emaciation, weakness, and death. The acute form will be described in the next paper (2).
Authors:
L PEARCE; W H BROWN
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of experimental medicine     Volume:  111     ISSN:  0022-1007     ISO Abbreviation:  J. Exp. Med.     Publication Date:  1960 Apr 
Date Detail:
Created Date:  1961-12-01     Completed Date:  1998-11-01     Revised Date:  2014-08-12    
Medline Journal Info:
Nlm Unique ID:  2985109R     Medline TA:  J Exp Med     Country:  Not Available    
Other Details:
Languages:  eng     Pagination:  485-504     Citation Subset:  OM    
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MeSH Terms
Descriptor/Qualifier:
Aging*
Disease*
Rabbits*
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): J Exp Med
ISSN: 0022-1007
ISSN: 1540-9538
Publisher: The Rockefeller University Press
Article Information
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©Copyright 1960, by The Rockefeller Institute
Received Day: 30 Month: 11 Year: 1959
Print publication date: Day: 31 Month: 3 Year: 1960
Volume: 111 Issue: 4
First Page: 485 Last Page: 504
ID: 2137272
PubMed Id: 13733754

HEREDITARY PREMATURE SENESCENCE OF THE RABBIT : I. CHRONIC FORM; GENERAL FEATURES
Louise Pearce
Wade H. Brown
From The Rockefeller Institute


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