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Hereditary premature senescence of the rabbit. II. Acute form; general features.
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MedLine Citation:
PMID:  13733753     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The acute form of hereditary premature senescence in 79 rabbits, among which the 20th generation of the condition was represented, has been described. The manifestations did not differ in kind from those previously described in connection with the chronic form (1) of the complex but their degree and, in particular, the severity and the rate of progression of systemic degeneration were much greater. The rabbits either did not survive to 2 years 6 months, of age or their physical condition had become critical by this time. A senile appearance, largely due to deteriorative changes of the coat, was frequently observed. The essential nature of the senescence condition was obviously a degeneration and one in which vital mechanisms essential to the maintenance of health were involved.
Authors:
L PEARCE; W H BROWN
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of experimental medicine     Volume:  111     ISSN:  0022-1007     ISO Abbreviation:  J. Exp. Med.     Publication Date:  1960 Apr 
Date Detail:
Created Date:  1961-12-01     Completed Date:  1998-11-01     Revised Date:  2014-08-12    
Medline Journal Info:
Nlm Unique ID:  2985109R     Medline TA:  J Exp Med     Country:  Not Available    
Other Details:
Languages:  eng     Pagination:  505-16     Citation Subset:  OM    
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MeSH Terms
Descriptor/Qualifier:
Aging*
Disease*
Rabbits*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): J Exp Med
ISSN: 0022-1007
ISSN: 1540-9538
Publisher: The Rockefeller University Press
Article Information
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©Copyright 1960, by The Rockefeller Institute
Received Day: 30 Month: 11 Year: 1959
Print publication date: Day: 31 Month: 3 Year: 1960
Volume: 111 Issue: 4
First Page: 505 Last Page: 516
ID: 2137268
PubMed Id: 13733753

HEREDITARY PREMATURE SENESCENCE OF THE RABBIT : II. ACUTE FORM; GENERAL FEATURES
Louise Pearce
Wade H. Brown
From The Rockefeller Institute


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