| Hereditary multi-infarct dementia. | |
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MedLine Citation:
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PMID: 3678285 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This paper summarizes the clinical and genetic features of a disease occurring in 16 patients from the same extended family, which resembles the multi-infarct dementia described by Sourander and Wålinder [Acta neuropath. 39: 247-254, 1977]. This family has relapsing strokes with neuropsychiatric symptoms, and they affect relatively young adult individuals of both sexes. The entity of the disease is characterized by autosomal dominant transmission with late onset and by association with occlusive cerebrovascular infarcts in the white matter, which was also generally reduced. Both of these features can be seen in the CT scan. In 13 members of this family the diagnosis can be regarded as certain and in a further 3 cases as more or less probable. |
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Authors:
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V Sonninen; M L Savontaus |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: European neurology Volume: 27 ISSN: 0014-3022 ISO Abbreviation: Eur. Neurol. Publication Date: 1987 |
Date Detail:
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Created Date: 1988-01-15 Completed Date: 1988-01-15 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0150760 Medline TA: Eur Neurol Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 209-15 Citation Subset: IM |
Affiliation:
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Department of Neurology, University of Turku, Finland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cerebral Infarction
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diagnosis,
genetics* Chromosome Aberrations / genetics Chromosome Disorders Dementia / diagnosis, genetics* Female Genes, Dominant Humans Middle Aged Pedigree Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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