Document Detail

Hereditary hemorrhagic telangiectasia and pregnancy.
MedLine Citation:
PMID:  17666633     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Hereditary hemorrhagic telangiectasia is a rare but life-threatening disease characterized by telangiectasias and arteriovenous malformations in different organs. When it is associated with pregnancy, this disease causes significant morbidity and mortality. CASE: We describe the pregnancy course of a primigravida with severe hereditary hemorrhagic telangiectasia. Her antepartum course was complicated by reduced pulmonary function, mild tricuspid regurgitation, and mild pulmonary hypertension. An amniocentesis was performed at the 32nd week for hydramnios. Because of a nonreassuring fetal heart rate pattern, she was delivered by cesarean of a female infant. At the beginning of the postpartum period, her pulmonary function spontaneously improved, and mother and female infant were discharged in good condition. CONCLUSION: Pregnancy is complicated in women with severe hereditary hemorrhagic telangiectasia, but can be managed successfully.
Christof Worda; Irene Lang; Peter Husslein; Meinhard Kneussl
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  110     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-01     Completed Date:  2007-09-06     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  474-7     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, Vienna General Hospital, Medical University of Vienna, Vienna, Austria.
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MeSH Terms
Cesarean Section
Infant, Newborn
Lung / blood supply,  physiopathology*
Polyhydramnios / diagnosis,  therapy
Pregnancy Complications, Cardiovascular / genetics*,  therapy
Pregnancy Outcome
Telangiectasia, Hereditary Hemorrhagic / complications*,  therapy
Uterus / blood supply

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