Document Detail


Hereditary elliptocytosis with a spectrin molecular defect in a white patient.
MedLine Citation:
PMID:  6426236     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
According to recent works, hereditary elliptocytosis (HE) appears to be related in some instances, to a defective self-association of spectrin (type I HE). We report a new case of type I HE observed in a white patient. Study of limited tryptic digestion of a spectrin dimer showed modification of a peptide involved in the dimer self-association process.
Authors:
M C Lecomte; D Dhermy; M Garbarz; H Gautero; O Bournier; C Galand; P Boivin
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta haematologica     Volume:  71     ISSN:  0001-5792     ISO Abbreviation:  Acta Haematol.     Publication Date:  1984  
Date Detail:
Created Date:  1984-06-11     Completed Date:  1984-06-11     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0141053     Medline TA:  Acta Haematol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  235-40     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Chemical Phenomena
Chemistry
Electrophoresis, Polyacrylamide Gel
Elliptocytosis, Hereditary / blood*
Female
Humans
Membrane Proteins / isolation & purification
Polymers
Spectrin / biosynthesis*
Trypsin / pharmacology
Chemical
Reg. No./Substance:
0/Membrane Proteins; 0/Polymers; 12634-43-4/Spectrin; EC 3.4.21.4/Trypsin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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