Document Detail


Hereditary disorders in Saguenay-Lac-St-Jean (Quebec, Canada).
MedLine Citation:
PMID:  1937486     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Saguenay-Lac-St-Jean is a geographically isolated region located in northeastern Quebec. Opened to the white settlement in 1938, its immigrants mainly came from Charlevoix, another isolated region of Quebec. The prevalence and/or incidence of several autosomal dominant and recessive disorders are very high. The overall birth prevalence of the recessive disorders was calculated at 1/207 living births and the overall carrier rate at 1/7 inhabitants. This situation may be explained by migration and social factors.
Authors:
M De Braekeleer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Human heredity     Volume:  41     ISSN:  0001-5652     ISO Abbreviation:  Hum. Hered.     Publication Date:  1991  
Date Detail:
Created Date:  1991-12-06     Completed Date:  1991-12-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0200525     Medline TA:  Hum Hered     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  141-6     Citation Subset:  IM    
Affiliation:
SOREP, Université du Québec à Chicoutimi, Canada.
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MeSH Terms
Descriptor/Qualifier:
Genes, Dominant
Genes, Recessive
Genetic Diseases, Inborn / epidemiology*
Genetics, Population
Humans
Incidence
Prevalence
Quebec / epidemiology
Rural Health

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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