Document Detail


HEREDITARY ANGIONEUROTIC EDEMA: TWO GENETIC VARIANTS.
MedLine Citation:
PMID:  14277836     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Serums of patients with hereditary angioneurotic edema lack inhibitory activity against the esterase derived from the first component of complement. In one group of patients this lack appears to result from failure to synthesize the esterase inhibitor of the first component of complement, whereas in another group of patients an abnormal, nonfunctional protein is synthesized.
Authors:
F S ROSEN; J PENSKY; V DONALDSON; P CHARACHE
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Science (New York, N.Y.)     Volume:  148     ISSN:  0036-8075     ISO Abbreviation:  Science     Publication Date:  1965 May 
Date Detail:
Created Date:  1965-07-01     Completed Date:  1996-12-01     Revised Date:  2011-11-30    
Medline Journal Info:
Nlm Unique ID:  0404511     Medline TA:  Science     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  957-8     Citation Subset:  OM    
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MeSH Terms
Descriptor/Qualifier:
Alpha-Globulins*
Angioedema*
Blood*
Complement System Proteins*
Enzyme Inhibitors*
Esterases*
Genetics, Medical*
Immunodiffusion*
Immunoelectrophoresis*
Chemical
Reg. No./Substance:
0/Alpha-Globulins; 0/Enzyme Inhibitors; 9007-36-7/Complement System Proteins; EC 3.1.-/Esterases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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