Document Detail


Hereditary angioedema.
MedLine Citation:
PMID:  17039649     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hereditary angioedema (HAE) is a rare autosomal dominant disorder caused by a C1-inhibitor deficiency. It is characterized by potentially life-threatening recurrent episodes of angioedema of the skin and mucosa. Several recent studies have further elucidated the immunology of HAE implicating bradykinin, the key mediator of the contact system. This article reviews the pathophysiology, subtypes, and clinical features of HAE. Therapeutic approaches for various clinical situations (emergency and prophylactic regimens) are also discussed.
Authors:
Michael M Sachse; Amor Khachemoune; Kjetil K Guldbakke; Michael Kirschfink
Related Documents :
3591839 - Familial rhizomelic dysplasia: phenotypic variation or heterogeneity?
2808789 - Persistent skin ulcers, mutilations, and acro-osteolysis in hereditary sensory and auto...
16082159 - Unique cerebellar-cerebral form of autosomal recessive ataxia.
20695019 - Mutations in pex10 are a cause of autosomal recessive ataxia.
6509399 - Evidence that charcot-marie-tooth disease with tremor coincides with the roussy-levy sy...
8199789 - Familial cosegregation of major affective disorder and darier's disease (keratosis foll...
23723649 - Importance of rookshana karma (dehydrating therapy) in the management of transverse mye...
22459359 - Hypopigmented parapsoriasis en plaque, a new overlooked member of the parapsoriasis fam...
18603879 - Isolated tuberculosis of testis.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of drugs in dermatology : JDD     Volume:  5     ISSN:  1545-9616     ISO Abbreviation:  J Drugs Dermatol     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-10-16     Completed Date:  2006-11-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101160020     Medline TA:  J Drugs Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  848-52     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aminocaproic Acids / therapeutic use
Angioedema / classification,  diagnosis*,  genetics,  physiopathology,  therapy*
Danazol / therapeutic use
Emergency Treatment
Genetic Predisposition to Disease
Humans
Plasma
Chemical
Reg. No./Substance:
0/Aminocaproic Acids; 17230-88-5/Danazol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Successful treatment of hand and foot psoriasis with efalizumab therapy.
Next Document:  Topical diphenylcyclopropenone as a measure of immune competence in HIV-seropositive subjects.