Document Detail

Herbal products use during pregnancy: prevalence and predictors.
MedLine Citation:
PMID:  19326360     Owner:  NLM     Status:  MEDLINE    
PURPOSES: (1) Measure the prevalence of herbal product (HP) use, alone, and concomitantly with prescribed medications during pregnancy, (2) identify the most frequently consumed HP during gestation and (3) determine predictors of HP use at the beginning of pregnancy, and during the third trimester. METHODS: A questionnaire was mailed to 8505 women selected from the Quebec Pregnancy Registry which was created by the linkage of three administrative databases: RAMQ, Méd-Echo and ISQ. Women were eligible if they were continuously insured by the RAMQ drug plan for at least 12 months before the first day of gestation and during pregnancy, and if they gave birth to a live born between January 1998 and December 2003 in one of the Quebec's hospitals. Women with diabetes and psychoses, and women who delivered a baby with birth defects were selected first. Descriptive statistics and multivariate logistic regression models were used to analyse data. RESULTS: Of the 3354 women (39%) who answered the questionnaire, and were included in the study, nine per cent used HP during pregnancy. 69% of users took at least one prescribed medication concomitantly. Chamomile, green tea, peppermint and flax were the most frequently HP used. Multivariate analyses showed that body mass index (BMI), multivitamin use and one to three prescribed medications used before pregnancy were predictors of HP use at the beginning of pregnancy; adherent women, smokers and users of HP prior to pregnancy were predictors of HP use during the third trimester. CONCLUSION: HP use alone and concomitantly with prescribed medications during pregnancy is common, and needs to be addressed by health professionals.
Krystel Moussally; Driss Oraichi; Anick Bérard
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Pharmacoepidemiology and drug safety     Volume:  18     ISSN:  1099-1557     ISO Abbreviation:  Pharmacoepidemiol Drug Saf     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-08     Completed Date:  2009-08-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9208369     Medline TA:  Pharmacoepidemiol Drug Saf     Country:  England    
Other Details:
Languages:  eng     Pagination:  454-61     Citation Subset:  IM    
Faculty of Pharmacy, University of Montreal, Quebec, Canada.
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MeSH Terms
Drug Therapy, Combination
Herb-Drug Interactions
Maternal Behavior
Phytotherapy / adverse effects*
Plant Preparations / adverse effects*
Plants, Medicinal / adverse effects*
Pregnancy Trimesters
Prescription Drugs / adverse effects
Quebec / epidemiology
Registries / statistics & numerical data
Women's Health
Reg. No./Substance:
0/Plant Preparations; 0/Prescription Drugs

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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