Document Detail


Herbal hepatoxicity from Chinese skullcap: A case report.
MedLine Citation:
PMID:  22855699     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
The use of herbal supplements has increased considerably over the last decade. We report a case of an elderly woman who began taking Move Free Advanced for arthritis, which in addition to glucosamine and chondroitin, contained two herbal ingredients, Chinese skullcap and Black Catechu. Our patient presented with significant cholestasis and hepatitis which significantly improved after discontinuation of the supplement. Since neither the patient nor the treating physician recognized this supplement as a potential hepatotoxin, she resumed taking the supplement and again suffered from considerable hepatotoxicity. Liver biopsy at that time was consistent with acute drug induced liver injury. She, once again, recovered after discontinuation of the supplement. Review of the literature confirms that Chinese skullcap has been implicated as a possible hepatotoxic agent which was demonstrated in this case.
Authors:
Leslie Yang; Andrew Aronsohn; John Hart; Donald Jensen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of hepatology     Volume:  4     ISSN:  1948-5182     ISO Abbreviation:  World J Hepatol     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-08-02     Completed Date:  2012-10-02     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  101532469     Medline TA:  World J Hepatol     Country:  China    
Other Details:
Languages:  eng     Pagination:  231-3     Citation Subset:  -    
Affiliation:
Leslie Yang, University of Chicago Medical Center Section of Gastroenterology, Chicago, IL 60637, United States.
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