| Hepatorenal injury induced by cutaneous application of Atractylis gummifera L. | |
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MedLine Citation:
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PMID: 20615152 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: In Mediterranean countries, intoxication by Atractylis gummifera L. is frequent and characterized principally by hepatorenal injury, often fatal. Its toxicity after a cutaneous application is unknown. We report a case of poisoning by A. gummifera L. induced by repeated cutaneous application. CASE REPORT: A 30-month-old boy was admitted in our pediatric intensive care unit in coma (Glasgow Coma Scale 8). Investigations showed hepatic cellular injury, cholestasis, decreased prothrombin level, and increased creatinine. History from the parents revealed repeated and occlusive cutaneous application of A. gummifera L. on a skin burn. Qualitative analysis of urine confirmed the diagnosis of A. gummifera poisoning. The child was discharged after 16 days of hospitalization with residual renal insufficiency. DISCUSSION: Poisoning by A. gummifera L. after cutaneous application has not previously been reported in the literature. The prevention of this poisoning, particularly frequent in Mediterranean countries, is mainly based on the education of the public concerning the dangers of this plant. |
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Authors:
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Asma Bouziri; Asma Hamdi; Khaled Menif; Nejla Ben Jaballah |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Clinical toxicology (Philadelphia, Pa.) Volume: 48 ISSN: 1556-9519 ISO Abbreviation: Clin Toxicol (Phila) Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-09-20 Completed Date: 2010-10-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101241654 Medline TA: Clin Toxicol (Phila) Country: England |
Other Details:
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Languages: eng Pagination: 752-4 Citation Subset: AIM; IM |
Affiliation:
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Pediatric Intensive Care Unit, Children's Hospital of Tunis, Tunis, Tunisia. asma.bouziri@yahoo.fr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Atractylis
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poisoning* Atractyloside / poisoning Child, Preschool Humans Liver / drug effects* Male Plant Poisoning / diagnosis, etiology* Renal Insufficiency / chemically induced* |
| Chemical | |
Reg. No./Substance:
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17754-44-8/Atractyloside |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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